SCHEMBL30869710

SCHEMBL30869710

Oc1ccc(-c2ccc3c(c2)Oc2cc(-c4ccc5[nH]ccc5c4)ccc2N3CCN2CCOCC2)cc1C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 2/20 0.38
PRKDC P78527 1/20 0.36
ABL1 P00519 1/20 0.35
BCR P11274 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CDK8 P49336 2/20 0.34
CD274 Q9NZQ7 1/20 0.34
CYP2C9 P11712 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
ATR Q13535 1/20 0.34
GRIA1 P42261 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869693 0.93 WDR5 (0.36) WDR5PRKDCABL1BCRALDH1A1
SCHEMBL30869516 0.90 CD274 (0.41) WDR5CDK8CD274PIK3CAMTOR
SCHEMBL32682881 0.89 WDR5 (0.43) WDR5PRKDCABL1BCRALDH1A1
SCHEMBL30869719 0.83 KDM1A (0.42) PRKDCALDH1A1MAPTHSD17B10CYP2C9
SCHEMBL30869633 0.83 CTSS (0.39) WDR5CDK8PIK3CAMTORMEN1
SCHEMBL30869715 0.82 PRKDC (0.40) PRKDCALDH1A1MAPTHSD17B10CDK8
SCHEMBL30869460 0.82 WDR5 (0.42) WDR5PRKDCABL1BCRALDH1A1
SCHEMBL30869568 0.81 CYP1A2 (0.38) ABL1ALDH1A1MAPTHSD17B10CD274
SCHEMBL27327784 0.81 CYP1A2 (0.38) ABL1ALDH1A1MAPTHSD17B10CD274
SCHEMBL30869480 0.78 PRKDC (0.37) PRKDCABL1CD274CYP2C9PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed