SCHEMBL30869715

SCHEMBL30869715

Brc1ccc2c(c1)Oc1cc(-c3ccc4[nH]ccc4c3)ccc1N2CCN1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.40
AHR P35869 2/20 0.40
CYP2A6 P11509 1/20 0.40
NR4A2 P43354 1/20 0.40
PIM1 P11309 1/20 0.38
ALDH1A1 P00352 2/20 0.38
PIK3CA P42336 2/20 0.38
CYP2C9 P11712 1/20 0.38
MTOR P42345 1/20 0.38
ATR Q13535 1/20 0.38
MEN1 O00255 1/20 0.37
TDP2 O95551 1/20 0.37
CFTR P13569 1/20 0.37
CASP6 P55212 1/20 0.37
KMT2A Q03164 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
GOPC Q9HD26 1/20 0.37
JAK2 O60674 1/20 0.37
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869459 0.90 PIM1 (0.45) PRKDCAHRCYP2A6NR4A2PIM1
SCHEMBL30869719 0.89 KDM1A (0.42) PRKDCALDH1A1PIK3CACYP2C9MTOR
SCHEMBL30869480 0.84 PRKDC (0.37) PRKDCPIM1PIK3CACYP2C9MTOR
SCHEMBL30869710 0.82 WDR5 (0.38) PRKDCALDH1A1PIK3CACYP2C9MTOR
SCHEMBL30869597 0.82 PIM1 (0.50) PIM1ALDH1A1MEN1TDP2CFTR
SCHEMBL32682881 0.80 WDR5 (0.43) PRKDCALDH1A1PIK3CACYP2C9MTOR
SCHEMBL30869516 0.79 CD274 (0.41) PIK3CAMTORJAK2EGFRFLT1
SCHEMBL30869456 0.77 EGFR (0.53) PIM1PIK3CACYP2C9JAK2EGFR
SCHEMBL30869488 0.77 EGFR (0.40) PRKDCALDH1A1PIK3CACYP2C9MTOR
SCHEMBL30869770 0.76 PRKDC (0.37) PRKDCPIM1PIK3CACYP2C9MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed