SCHEMBL30869719

SCHEMBL30869719

c1ccc2c(c1)Oc1cc(-c3ccc4[nH]ccc4c3)ccc1N2CCN1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.42
NPC1 O15118 1/20 0.41
PRKDC P78527 2/20 0.41
DRD2 P14416 2/20 0.41
DRD3 P35462 2/20 0.41
DRD4 P21917 1/20 0.41
PIK3CA P42336 3/20 0.38
MTOR P42345 3/20 0.38
CYP2C9 P11712 1/20 0.38
ATR Q13535 1/20 0.38
JAK2 O60674 1/20 0.37
CASP3 P42574 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CDK2 P24941 1/20 0.37
PRKCZ Q05513 1/20 0.37
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869715 0.89 PRKDC (0.40) NPC1PRKDCPIK3CAMTORCYP2C9
SCHEMBL30869480 0.84 PRKDC (0.37) PRKDCDRD2DRD3DRD4PIK3CA
SCHEMBL30869710 0.83 WDR5 (0.38) PRKDCPIK3CAMTORCYP2C9ATR
SCHEMBL30869459 0.82 PIM1 (0.45) NPC1PRKDCPIK3CAMTORCYP2C9
SCHEMBL32682881 0.81 WDR5 (0.43) PRKDCPIK3CAMTORCYP2C9ATR
SCHEMBL30869633 0.81 CTSS (0.39) DRD2DRD3DRD4PIK3CAMTOR
SCHEMBL30869516 0.80 CD274 (0.41) PIK3CAMTORJAK2EGFRFLT1
SCHEMBL30869488 0.79 EGFR (0.40) PRKDCPIK3CAMTORCYP2C9ATR
SCHEMBL30869770 0.79 PRKDC (0.37) PRKDCDRD2DRD3DRD4PIK3CA
SCHEMBL30869782 0.79 CHRNA7 (0.38) PRKDCPIK3CAMTORCYP2C9ATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed