SCHEMBL30869724

SCHEMBL30869724

FC(F)(F)c1ccc2c(c1OCc1ccccc1)Oc1ccc(-c3ccc4[nH]ccc4c3)cc1N2CCN1CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRPK1 Q96SB4 2/20 0.36
ENPP2 Q13822 1/20 0.35
CDK8 P49336 1/20 0.35
MCHR1 Q99705 2/20 0.34
MC4R P32245 1/20 0.34
PIK3CA P42336 3/20 0.34
MTOR P42345 2/20 0.34
DRD4 P21917 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
WDR5 P61964 1/20 0.33
EGFR P00533 1/20 0.33
FLT1 P17948 1/20 0.33
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869742 0.89 CTSS (0.39) SRPK1ENPP2CDK8MCHR1MC4R
SCHEMBL30869633 0.84 CTSS (0.39) SRPK1ENPP2CDK8MCHR1MC4R
SCHEMBL30869693 0.79 WDR5 (0.36) CDK8PIK3CAMTORALDH1A1WDR5
SCHEMBL30869460 0.79 WDR5 (0.42) SRPK1CDK8PIK3CAMTORALDH1A1
SCHEMBL30869782 0.77 CHRNA7 (0.38) PIK3CAMTORALDH1A1EGFRFLT1
SCHEMBL30869625 0.75 WDR5 (0.42) SRPK1CDK8PIK3CAALDH1A1WDR5
SCHEMBL30869719 0.75 KDM1A (0.42) PIK3CAMTORDRD4ALDH1A1EGFR
SCHEMBL30869710 0.74 WDR5 (0.38) SRPK1CDK8PIK3CAMTORALDH1A1
SCHEMBL30869459 0.74 PIM1 (0.45) PIK3CAMTORALDH1A1EGFRFLT1
SCHEMBL32682881 0.74 WDR5 (0.43) SRPK1CDK8PIK3CAMTORALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed