SCHEMBL30869459

SCHEMBL30869459

Brc1ccc2c(c1)N(CCN1CCOCC1)c1cc(-c3ccc4[nH]ccc4c3)ccc1O2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.45
PRKDC P78527 2/20 0.40
CYP2A6 P11509 1/20 0.40
AHR P35869 1/20 0.40
NR4A2 P43354 1/20 0.40
PIK3CA P42336 2/20 0.38
CYP2C9 P11712 1/20 0.38
MTOR P42345 1/20 0.38
ATR Q13535 1/20 0.38
JAK2 O60674 1/20 0.37
CREBBP Q92793 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EGFR P00533 1/20 0.36
FLT1 P17948 1/20 0.36
CNR1 P21554 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869715 0.90 PRKDC (0.40) PIM1PRKDCCYP2A6AHRNR4A2
SCHEMBL30869488 0.84 EGFR (0.40) PRKDCPIK3CACYP2C9MTORATR
SCHEMBL30869770 0.84 PRKDC (0.37) PIM1PRKDCPIK3CACYP2C9MTOR
SCHEMBL30869782 0.84 CHRNA7 (0.38) PRKDCPIK3CACYP2C9MTORATR
SCHEMBL30869719 0.82 KDM1A (0.42) PRKDCPIK3CACYP2C9MTORATR
SCHEMBL30869693 0.82 WDR5 (0.36) PRKDCPIK3CACYP2C9MTORATR
SCHEMBL30869460 0.80 WDR5 (0.42) PRKDCPIK3CACYP2C9MTORATR
SCHEMBL30869625 0.77 WDR5 (0.42) PIK3CACREBBPALDH1A1MAPTHSD17B10
SCHEMBL30869480 0.76 PRKDC (0.37) PIM1PRKDCPIK3CACYP2C9MTOR
SCHEMBL30869710 0.74 WDR5 (0.38) PRKDCPIK3CACYP2C9MTORATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed