SCHEMBL30869494

SCHEMBL30869494

C[C@@]12COC[C@]1(C)CN(CC(=O)N1c3ccc(Br)cc3Oc3cc(Br)ccc31)C2

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CUL4A Q13619 1/20 0.33
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
XIAP P98170 1/20 0.31
BIRC2 Q13490 1/20 0.31
ANPEP P15144 3/20 0.31
CASP2 P42575 1/20 0.31
AHR P35869 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
NPC1 O15118 1/20 0.30
TDP2 O95551 1/20 0.30
CFTR P13569 1/20 0.30
CASP6 P55212 1/20 0.30
HKDC1 Q2TB90 1/20 0.30
GOPC Q9HD26 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869733 0.78 PIM1 (0.40) AHRMEN1KMT2ATDP2CFTR
SCHEMBL30869541 0.76 PIM1 (0.34) AHR
SCHEMBL30869539 0.76 PIM1 (0.34) AHR
SCHEMBL30869434 0.71 CASP2 (0.45) CUL4AMAPTCASP2AHRNPC1
SCHEMBL30869566 0.69 PIM1 (0.32)
SCHEMBL30869767 0.69 TSHR (0.47) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL30869419 0.68 GRM2 (0.35) LMNAXIAPBIRC2
SCHEMBL30869661 0.66 WNT1 (0.35) CUL4A
SCHEMBL30869712 0.65 PIM1 (0.41) LMNAMAPTAHRALDH1A1MEN1
SCHEMBL30869631 0.64 PIM1 (0.35) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 CUL4A 3034/4885LMNA 2249/4885MAPT 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.