SCHEMBL30869747

SCHEMBL30869747

Cc1cc2c(cc1Br)Oc1cc(Br)cnc1N2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.32
BCHE P06276 1/20 0.30
CES1 P23141 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869709 1.00 AHR (0.32) AHRBCHECES1SMN1; SMN2
SCHEMBL30869696 0.79 MMP12 (0.38) AHRSMN1; SMN2
SCHEMBL30869620 0.79 AHR (0.38) AHRSMN1; SMN2
SCHEMBL30869424 0.79 AHR (0.38) AHRSMN1; SMN2
SCHEMBL30869584 0.78 AHR (0.42) AHRCES1
SCHEMBL30869575 0.78 AHR (0.42) AHRCES1
SCHEMBL30869514 0.64 ALDH1A1 (0.33)
SCHEMBL27325923 0.64 VRK1 (0.50)
SCHEMBL38661474 0.63 ALOX5 (0.39)
SCHEMBL6466406 0.63 AHR (0.68) AHRBCHECES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed