SCHEMBL30869709

SCHEMBL30869709

Cc1cc2c(cc1Br)Oc1cc(Br)cnc1N2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.32
BCHE P06276 1/20 0.30
CES1 P23141 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869747 1.00 AHR (0.32) AHRBCHECES1SMN1; SMN2
SCHEMBL30869696 0.79 MMP12 (0.38) AHRSMN1; SMN2
SCHEMBL30869620 0.79 AHR (0.38) AHRSMN1; SMN2
SCHEMBL30869424 0.79 AHR (0.38) AHRSMN1; SMN2
SCHEMBL30869584 0.78 AHR (0.42) AHRCES1
SCHEMBL30869575 0.78 AHR (0.42) AHRCES1
SCHEMBL30869514 0.64 ALDH1A1 (0.33)
SCHEMBL27325923 0.64 VRK1 (0.50)
SCHEMBL38661474 0.63 ALOX5 (0.39)
SCHEMBL6466406 0.63 AHR (0.68) AHRBCHECES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 AHR 4553/4885BCHE 4450/4885CES1 2718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.