SCHEMBL30869800

SCHEMBL30869800

c1cc2c(cc1-c1cncc3c1cnn3C1CCCCO1)Oc1cc(-c3cncc4c3cnn4C3CCCCO3)ccc1N2CCN1CC2(COC2)C1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
BRD4 O60885 3/20 0.34
CREBBP Q92793 3/20 0.34
ACVRL1 P37023 1/20 0.32
ACVR1 Q04771 1/20 0.32
ATR Q13535 2/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869686 0.86 ATR (0.34) RXRARXRBRXRGBRD4CREBBP
SCHEMBL30869682 0.80 ATR (0.35) RXRARXRBRXRGACVRL1ACVR1
SCHEMBL30869528 0.76 CD274 (0.39) BRD4CREBBPACVR1ATRCD274
SCHEMBL32682878 0.75 BRD4 (0.34) BRD4CREBBPATR
SCHEMBL30869853 0.74 ABL1 (0.36)
SCHEMBL30869614 0.71 RXRA (0.34) RXRARXRBRXRGACVRL1ACVR1
SCHEMBL30869723 0.68 PRKCQ (0.42) BRD4
SCHEMBL30869841 0.65 PDE10A (0.37) CD274
SCHEMBL32682876 0.65 KDM1A (0.39) ATR
SCHEMBL30869445 0.64 GRIA1 (0.43) ACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed