SCHEMBL30869686

SCHEMBL30869686

c1cc(-c2ccc3c(c2)Oc2cc(-c4ccnc5c4cnn5C4CCCCO4)ccc2N3CCN2CC3(COC3)C2)c2cnn(C3CCCCO3)c2n1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ATR Q13535 15/20 0.34
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
TBK1 Q9UHD2 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
CD274 Q9NZQ7 1/20 0.31
CAMKK1 Q8N5S9 1/20 0.31
CAMKK2 Q96RR4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869528 0.90 CD274 (0.39) ATRBRD4CREBBPCD274
SCHEMBL30869800 0.86 RXRA (0.35) ATRBRD4CREBBPRXRARXRB
SCHEMBL30869532 0.81 ATR (0.38) ATRRXRARXRBRXRG
SCHEMBL30869663 0.80 CD274 (0.39) ATRCD274
SCHEMBL30869723 0.77 PRKCQ (0.42) BRD4
SCHEMBL30869421 0.72 ATR (0.33) ATR
SCHEMBL30869841 0.67 PDE10A (0.37) CD274
SCHEMBL30897220 0.66 CYP4F2 (0.43) ATRRXRARXRBRXRG
SCHEMBL25222791 0.65 CYP4F2 (0.42) ATRRXRARXRBRXRG
SCHEMBL19464040 0.65 ALDH1A1 (0.46) ATRRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed