SCHEMBL30869853

SCHEMBL30869853

c1cc2c(cc1-c1cncc3[nH]ncc13)Oc1cc(-c3cncc4[nH]ncc34)ccc1N2CCN1CC2(COC2)C1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.36
BACE1 P56817 1/20 0.33
GRIA1 P42261 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
CD38 P28907 1/20 0.32
PIK3CG P48736 1/20 0.31
PIM1 P11309 1/20 0.31
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869717 0.86 PIK3CG (0.41) ABL1PIK3CGPIM1PIK3CA
SCHEMBL30869445 0.82 GRIA1 (0.43) ABL1BACE1GRIA1CD38PIM1
SCHEMBL30869723 0.82 PRKCQ (0.42) CD38PIK3CA
SCHEMBL30869796 0.77 GRIA1 (0.42) ABL1BACE1GRIA1PIM1
SCHEMBL30869426 0.77 GRIA1 (0.42) ABL1BACE1GRIA1CD38PIM1
SCHEMBL30869841 0.77 PDE10A (0.37) ABL1GRIA1CD38PIM1PIK3CA
SCHEMBL30869822 0.76 GRIA1 (0.41) ABL1BACE1GRIA1PIM1
SCHEMBL30869510 0.75 BRAF (0.41) ABL1
SCHEMBL30869800 0.74 RXRA (0.35)
SCHEMBL30869578 0.73 BACE1 (0.41) BACE1GRIA1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed