SCHEMBL30869717

SCHEMBL30869717

c1cc2c(cc1-c1cncc3[nH]ncc13)Oc1cc(-c3cncc4[nH]ncc34)ccc1N2CCN1CCOCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.41
EGFR P00533 2/20 0.38
MAP4K4 O95819 1/20 0.38
ERBB2 P04626 1/20 0.38
MAPK9 P45984 1/20 0.38
CSNK1D P48730 1/20 0.38
PRKD2 Q9BZL6 1/20 0.38
SLK Q9H2G2 1/20 0.38
TDO2 P48775 2/20 0.37
PIM1 P11309 1/20 0.36
PIK3CA P42336 8/20 0.36
PIK3CD O00329 1/20 0.36
PIK3R1 P27986 1/20 0.36
ABL1 P00519 1/20 0.36
TGFBR1 P36897 1/20 0.35
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
METAP2 P50579 1/20 0.35
MTOR P42345 1/20 0.34
SMYD2 Q9NRG4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869853 0.86 ABL1 (0.36) PIK3CGPIM1PIK3CAABL1
SCHEMBL30869456 0.81 EGFR (0.53) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869877 0.81 PIK3CD (0.48) CSNK1DPIK3CAPIK3CDTGFBR1BRD4
SCHEMBL30869510 0.78 BRAF (0.41) ABL1
SCHEMBL30869756 0.77 PIK3CG (0.49) PIK3CGPIK3CAPIK3CDPIK3R1CREBBP
SCHEMBL30869734 0.76 EGFR (0.55) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869573 0.76 EGFR (0.53) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869570 0.76 EGFR (0.52) EGFRMAP4K4ERBB2MAPK9CSNK1D
SCHEMBL30869729 0.75 PIK3CG (0.48) PIK3CGPIK3CAPIK3CDPIK3R1CREBBP
SCHEMBL30869745 0.75 PDE10A (0.45) EGFRMAP4K4ERBB2MAPK9CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PIK3CG 159/4885EGFR 1355/4885MAP4K4 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.