Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 5/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25411583 | 0.91 | CCR2 (0.36) | ALDH1A1MAPK1SMN1; SMN2CCR2AKR1B1 | |
| SCHEMBL31458976 | 0.85 | LMNA (0.33) | ALDH1A1MAPK1SMN1; SMN2CBLBRAB9A | |
| SCHEMBL31274678 | 0.82 | POLB (0.33) | SMN1; SMN2CCR2CBLBRAB9AKMT2A | |
| SCHEMBL31459001 | 0.79 | MAPT (0.32) | ALDH1A1CCR2AKR1B1LMNAPOLB | |
| SCHEMBL31275111 | 0.79 | S1PR2 (0.39) | AKR1B1KMT2A | |
| SCHEMBL30872137 | 0.77 | TAS1R3 (0.39) | CCR2 | |
| SCHEMBL31459244 | 0.77 | S1PR2 (0.34) | CCR2RAB9ALMNA | |
| SCHEMBL25414277 | 0.75 | LMNA (0.36) | CCR2RAB9AKMT2ALMNA | |
| SCHEMBL30521337 | 0.74 | OPRM1 (0.41) | POLB | |
| SCHEMBL31251401 | 0.72 | CCR2 (0.43) | CCR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |