Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874805 | 0.80 | PIK3CB (0.42) | VNN1DPP4PIK3CAPIK3CDPIK3CB | |
| SCHEMBL30874909 | 0.77 | VNN1 (0.47) | VNN1DPP4 | |
| SCHEMBL12784949 | 0.73 | DPP4 (0.46) | VNN1DPP4SMN1; SMN2 | |
| SCHEMBL25753684 | 0.71 | POLB (0.46) | POLBLMNATP53GAAHTT | |
| SCHEMBL30874798 | 0.69 | VNN1 (0.62) | VNN1POLBDPP4 | |
| SCHEMBL30874862 | 0.68 | CYP19A1 (0.47) | VNN1DPP4SMN1; SMN2 | |
| SCHEMBL30874864 | 0.68 | VNN1 (0.47) | VNN1DPP4 | |
| SCHEMBL30874955 | 0.68 | DPP4 (0.42) | VNN1DPP4 | |
| SCHEMBL30874949 | 0.67 | ALDH1A1 (0.44) | VNN1DPP4 | |
| SCHEMBL30874948 | 0.67 | DPP4 (0.44) | VNN1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |