SCHEMBL3087491

SCHEMBL3087491

CC(S)CCC(=O)OCC(C)OC(=O)CCC(C)S

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.36
PRKCA P17252 2/20 0.36
PRKCE Q02156 2/20 0.36
PRKCQ Q04759 2/20 0.36
PRKCD Q05655 2/20 0.36
TSHR P16473 2/20 0.35
CYP3A4 P08684 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LPAR3 Q9UBY5 5/20 0.32
LPAR1 Q92633 3/20 0.32
ENPP2 Q13822 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LPAR2 Q9HBW0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003547 0.84 ADRA2A (0.34) LMNAALDH1A1MAPT
SCHEMBL98334 0.81 LMNA (0.41) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL6002424 0.81 ALDH1A1 (0.50) LMNAALDH1A1PRKCAPRKCEPRKCQ
SCHEMBL2402716 0.79 LMNA (0.50) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL1171277 0.78 DGKA (0.43) MAPTTSHRCYP3A4ATMTDP1
SCHEMBL3086359 0.78 LMNA (0.46) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL17964469 0.77 ALDH1A1 (0.41) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL3212549 0.77 TLR2 (0.37) ALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL98666 0.77 PRKCA (0.43) LMNAALDH1A1MAPTPRKCATSHR
SCHEMBL11679497 0.77 EGLN1 (0.41) LMNAALDH1A1MAPTPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283095-B2 Thiourethane compound and photosensitive resin composition SHOWA DENKO K.K. (JP) 2012-10-09 US disclosed
US-20100233596-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2010-09-16 US disclosed
EP-2055726-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Showa Denko K.K. (JP) 2009-05-06 EP disclosed
US-20060036023-A1 Color filter black matrix resist composition SHOWA DENKO K.K. (JP) 2006-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233596-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION RCOR3, CBR3, TAS2R3 LMNA 4454/4885ALDH1A1 1341/4885MAPT 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.