Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679552 | 0.85 | HDAC1 (0.37) | TSHRF2NPSR1HDAC1HDAC8 | |
| SCHEMBL1600710 | 0.84 | HDAC8 (0.41) | MTNR1AMTNR1BRIPK1CTSBCTSS | |
| SCHEMBL16141841 | 0.84 | L3MBTL1 (0.38) | MTNR1BTSHRF2NPSR1HDAC1 | |
| SCHEMBL4878980 | 0.84 | TSHR (0.43) | TSHRF2HDAC1HDAC8HDAC6 | |
| SCHEMBL22264784 | 0.83 | MTNR1A (0.39) | MTNR1AMTNR1BRIPK1CTSBCTSS | |
| SCHEMBL2919371 | 0.82 | MTNR1A (0.40) | MTNR1AMTNR1BRIPK1CTSBCTSS | |
| SCHEMBL10401421 | 0.82 | MTNR1A (0.40) | MTNR1AMTNR1BRIPK1CTSBCTSS | |
| SCHEMBL31679532 | 0.81 | SMN1; SMN2 (0.43) | TSHRAAK1NPSR1L3MBTL1PTPN1 | |
| SCHEMBL31679530 | 0.81 | ALDH1A1 (0.48) | TSHRNPSR1 | |
| SCHEMBL4872329 | 0.80 | LMNA (0.41) | TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610262-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | Artivila Biopharma (CN) | 2025-09-03 | — | — | EP | disclosed |
| CN-117964628-A | Macrocyclic compounds as CDK9 inhibitors and application thereof | 科辉智药生物科技(深圳)有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024088189-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | 科辉智药生物科技（无锡）有限公司 | 2024-05-02 | — | — | WO | disclosed |