SCHEMBL30877211

SCHEMBL30877211

CC(C)CN(C)CCc1c[nH]c2c(F)cc(F)cc12

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.55
HTR2A P28223 4/20 0.47
MPO P05164 4/20 0.44
SLC6A4 P31645 2/20 0.39
HTR1A P08908 4/20 0.38
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29206391 0.87 GPR84 (0.52) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL30877232 0.87 HTR2A (0.42) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL30877288 0.87 GPR84 (0.52) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL29206492 0.87 HTR2A (0.42) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL30877287 0.85 GPR84 (0.56) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL29206395 0.85 GPR84 (0.56) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL31158591 0.85 MTNR1A (0.44) HTR2ASLC6A4HTR1AHTR1DHTR1B
SCHEMBL24692764 0.85 HTR2A (0.64) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL30877210 0.85 HTR2A (0.64) GPR84HTR2AMPOSLC6A4HTR1A
SCHEMBL30483767 0.84 GPR84 (0.63) GPR84HTR2AMPOSLC6A4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117957211-A Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof 圣约瑟夫大学 2024-04-30 CN claimed
US-20240286998-A1 FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME SAINT JOSEPH'S UNIVERSITY 2024-08-29 US disclosed
CN-117957211-A Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof 圣约瑟夫大学 2024-04-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240286998-A1 FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME TPH2, TPH1, HNMT GPR84 528/4885HTR2A 4/4885MPO 1666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.