Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | HTR1D | P28221 | 6/20 | 0.47 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR1E | P28566 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | HTR5A | P47898 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206468 | 1.00 | HTR1A (0.50) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL29206473 | 0.95 | HTR1A (0.54) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL25748619 | 0.91 | HTR1A (0.61) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL29206500 | 0.90 | MTNR1A (0.46) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL30877200 | 0.90 | MTNR1A (0.46) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL24694054 | 0.86 | HTR2A (0.52) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL25748004 | 0.86 | MTNR1A (0.59) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL31158584 | 0.85 | HTR1A (0.41) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL29206471 | 0.85 | HTR1A (0.41) | HTR1AHTR1DHTR1BHTR2AMTNR1A | |
| SCHEMBL30877243 | 0.85 | HTR1A (0.59) | HTR1AHTR1DHTR1BHTR2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | claimed |
| US-20240286998-A1 | FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | SAINT JOSEPH'S UNIVERSITY | 2024-08-29 | — | — | US | disclosed |
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240286998-A1 | FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | TPH2, TPH1, HNMT | HTR1A 9/4885HTR1D 27/4885HTR1B 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.