Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877344 | 0.80 | PIK3CD (0.35) | HTR6LMNATHRBHSD11B1MEN1 | |
| SCHEMBL30877437 | 0.79 | HTR6 (0.50) | HTR6LMNATHRBHSD11B1MEN1 | |
| SCHEMBL29131767 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL30877481 | 0.73 | DRD2 (0.48) | HTR6MEN1KMT2AATM | |
| SCHEMBL4671281 | 0.72 | HTR6 (0.76) | HTR6LMNATHRBSLC6A4 | |
| SCHEMBL30877462 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPT | |
| SCHEMBL30877425 | 0.72 | ALDH1A1 (0.44) | LMNAMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL28733308 | 0.72 | ALDH1A1 (0.47) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL30877446 | 0.71 | ALDH1A1 (0.40) | LMNAMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL4676869 | 0.70 | HTR6 (0.64) | HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |