Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 12/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877525 | 0.77 | RAPGEF4 (0.51) | DRD2DRD1HTR6KMT2AMEN1 | |
| SCHEMBL5440583 | 0.76 | HTR6 (0.80) | HTR6HTTCYP3A4CYP2D6 | |
| SCHEMBL28733308 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL5795139 | 0.73 | ALDH1A1 (0.45) | KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL30877378 | 0.73 | HTR6 (0.49) | ATMHTR6KMT2AMEN1 | |
| SCHEMBL30877533 | 0.71 | ACHE (0.43) | HTR6HTTL3MBTL1 | |
| SCHEMBL30877241 | 0.71 | MET (0.39) | DRD2DRD1HTR6CYP3A4 | |
| SCHEMBL30877436 | 0.70 | RAPGEF4 (0.43) | HTR6KMT2AL3MBTL1 | |
| SCHEMBL7564728 | 0.70 | KMT2A (0.84) | ATMKMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL9386579 | 0.70 | KMT2A (0.84) | ATMKMT2AMEN1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |