Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29179075 | 0.82 | RAPGEF4 (0.49) | RAPGEF4HSD11B1LMNATHRBKMT2A | |
| SCHEMBL30877338 | 0.80 | RAPGEF4 (0.47) | RAPGEF4HSD11B1LMNATHRBALDH1A1 | |
| SCHEMBL30877378 | 0.79 | HTR6 (0.49) | HTR6HSD11B1LMNATHRBKMT2A | |
| SCHEMBL29806024 | 0.73 | HTR6 (0.47) | HTR6RAPGEF4HSD11B1CA1CA2 | |
| SCHEMBL1521832 | 0.73 | QDPR (0.50) | HTR6LMNA | |
| SCHEMBL7678499 | 0.72 | RAPGEF4 (0.56) | HTR6RAPGEF4HSD11B1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8580869 | 0.71 | QDPR (0.49) | HTR6LMNA | |
| SCHEMBL29888784 | 0.71 | HTR6 (0.45) | HTR6RAPGEF4LMNAKMT2AMEN1 | |
| SCHEMBL30877247 | 0.70 | RAPGEF4 (0.51) | RAPGEF4LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL30877525 | 0.70 | RAPGEF4 (0.51) | HTR6RAPGEF4KMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |