Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879972 | 0.76 | PDE3B (0.39) | PIK3C3MAPK14CSNK1ECSNK1DATR | |
| SCHEMBL18857842 | 0.74 | MAPK14 (0.47) | PIK3CDPIK3CAMAPK14CSNK1ECSNK1D | |
| SCHEMBL2088246 | 0.71 | ACMSD (0.38) | — | |
| SCHEMBL9825294 | 0.69 | JAK2 (0.41) | — | |
| SCHEMBL14334928 | 0.69 | HRH3 (0.53) | — | |
| SCHEMBL17384805 | 0.68 | RAB9A (0.46) | PIK3C3MAPK14CSNK1ECSNK1D | |
| SCHEMBL4790461 | 0.68 | SIGMAR1 (0.60) | — | |
| SCHEMBL7143060 | 0.67 | MAPK14 (0.52) | PIK3CDPIK3CAMAPK14CSNK1ECSNK1D | |
| SCHEMBL14183094 | 0.67 | MAPK14 (0.48) | PIK3CDPIK3CAMAPK14CSNK1ECSNK1D | |
| SCHEMBL14320398 | 0.67 | BACE1 (0.42) | PIK3CDPIK3CAMAPK14CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |