Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | WDR5 | P61964 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879352 | 0.91 | WDR5 (0.58) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30879091 | 0.88 | WDR5 (0.55) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30878893 | 0.88 | NPSR1 (0.41) | ALDH1A1KMT2AGAALMNAMAPT | |
| SCHEMBL30879010 | 0.88 | LMNA (0.53) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30879011 | 0.81 | WDR5 (0.50) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30878851 | 0.80 | MAPT (0.51) | ALDH1A1KMT2AGAALMNAMAPT | |
| SCHEMBL30879222 | 0.78 | MAPT (0.44) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30878681 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30878800 | 0.76 | MAPT (0.42) | ALDH1A1KMT2AWDR5GAALMNA | |
| SCHEMBL30879069 | 0.75 | HTR1A (0.46) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |