Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 8/20 | 0.38 |
| ▸ | HTR7 | P34969 | 8/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879222 | 0.91 | MAPT (0.44) | NPSR1TSHRKMT2ALMNAPLA2G1B | |
| SCHEMBL30879203 | 0.88 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1MAPTMEN1 | |
| SCHEMBL30878800 | 0.88 | MAPT (0.42) | NPSR1TSHRKMT2ALMNAPLA2G1B | |
| SCHEMBL30879069 | 0.87 | HTR1A (0.46) | NPSR1TSHRKMT2ALMNAPLA2G1B | |
| SCHEMBL30879352 | 0.78 | WDR5 (0.58) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30879219 | 0.77 | HTR7 (0.43) | HTR1AHTR7MAPT | |
| SCHEMBL30879091 | 0.76 | WDR5 (0.55) | KMT2ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30879010 | 0.75 | LMNA (0.53) | KMT2ALMNAHTR1AHTR7PDE4B | |
| SCHEMBL30878891 | 0.73 | KDM4E (0.36) | KMT2ALMNAHTR7ALDH1A1MAPT | |
| SCHEMBL30879177 | 0.72 | HDAC3 (0.44) | KMT2AALDH1A1MAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |