Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204829 | 1.00 | XPO1 (0.66) | XPO1HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL29204826 | 0.92 | WDR5 (0.57) | XPO1HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL30883146 | 0.86 | XPO1 (0.88) | XPO1MEN1KMT2AMAPK1USP2 | |
| SCHEMBL29204805 | 0.86 | XPO1 (0.88) | XPO1MEN1KMT2AMAPK1USP2 | |
| SCHEMBL29204830 | 0.85 | XPO1 (0.69) | XPO1HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL30883143 | 0.85 | XPO1 (0.69) | XPO1HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL29204806 | 0.81 | WDR5 (0.61) | XPO1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL30883139 | 0.80 | XPO1 (0.77) | XPO1MEN1KMT2AUSP2TP53 | |
| SCHEMBL29204831 | 0.80 | XPO1 (0.77) | XPO1MEN1KMT2AUSP2TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL9035256 | 0.80 | HTR1D (0.66) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |