Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29598198 | 0.80 | MEN1 (0.49) | NAAAHSD11B1LMNASMN1; SMN2OPRM1 | |
| SCHEMBL21544698 | 0.78 | NAAA (0.50) | NAAAHSD11B1LMNASMN1; SMN2OPRM1 | |
| SCHEMBL25387067 | 0.76 | NAAA (0.52) | NAAAHSD11B1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18043699 | 0.73 | CA1 (0.55) | NAAASLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL22362684 | 0.71 | LMNA (0.48) | NAAAHSD11B1LMNASMN1; SMN2 | |
| SCHEMBL22027030 | 0.71 | NAAA (0.44) | NAAAHSD11B1LMNASMN1; SMN2OPRM1 | |
| SCHEMBL22026919 | 0.70 | NAAA (0.46) | NAAAHSD11B1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL25386527 | 0.69 | CA12 (0.41) | NAAAHSD11B1LMNASLC6A4SLC6A3 | |
| SCHEMBL22027090 | 0.68 | NAAA (0.47) | NAAAHSD11B1LMNASMN1; SMN2POLB | |
| SCHEMBL3712653 | 0.67 | HDAC3 (0.61) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |