Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.44 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.44 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22027200 | 0.94 | KMT2A (0.45) | NAAAKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL22027277 | 0.90 | DGAT1 (0.46) | NAAAKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL21544698 | 0.88 | NAAA (0.50) | NAAAKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL22026919 | 0.86 | NAAA (0.46) | NAAALMNASMN1; SMN2HSD11B1CA1 | |
| SCHEMBL22027090 | 0.83 | NAAA (0.47) | NAAAKMT2ALMNASMN1; SMN2HSD11B1 | |
| SCHEMBL22026882 | 0.81 | LMNA (0.45) | NAAAKMT2ALMNASMN1; SMN2HSD11B1 | |
| SCHEMBL21805979 | 0.79 | ATM (0.44) | NAAAKMT2ALMNASMN1; SMN2CA1 | |
| SCHEMBL22026922 | 0.79 | SMN1; SMN2 (0.46) | NAAAKMT2ALMNASMN1; SMN2HSD11B1 | |
| SCHEMBL12936217 | 0.78 | KMT2A (0.66) | KMT2ALMNASMN1; SMN2HSD11B1 | |
| SCHEMBL25387067 | 0.77 | NAAA (0.52) | NAAALMNASMN1; SMN2HSD11B1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2022-01-06 | — | — | US | disclosed |
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2022-01-06 | — | — | US | disclosed |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2020-06-11 | — | — | US | disclosed |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | AOX1, AOC2, MAOA | NAAA 720/4885KMT2A 3212/4885TET3 1573/4885 |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | AOX1, AOC2, MAOA | NAAA 720/4885KMT2A 3212/4885TET3 1573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.