Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28392276 | 0.81 | LMNA (0.43) | LMNAMAPTNAAASMN1; SMN2CNR2 | |
| SCHEMBL21220171 | 0.79 | MEN1 (0.40) | SMN1; SMN2L3MBTL1EPHX2CYP1A2KMT2A | |
| SCHEMBL22362680 | 0.78 | ATF4 (0.44) | HSD11B1KMT2A | |
| SCHEMBL21544698 | 0.78 | NAAA (0.50) | LMNAMAPTNAAASMN1; SMN2CA1 | |
| SCHEMBL25387067 | 0.77 | NAAA (0.52) | LMNAMAPTNAAASMN1; SMN2CA1 | |
| SCHEMBL18043699 | 0.76 | CA1 (0.55) | MAPTNAAACA1CA2ATM | |
| SCHEMBL17924794 | 0.73 | OPRM1 (0.46) | ATML3MBTL1NPC1RAB9AMAPK1 | |
| SCHEMBL29598198 | 0.71 | MEN1 (0.49) | LMNANAAASMN1; SMN2CA1CA2 | |
| SCHEMBL22027030 | 0.71 | NAAA (0.44) | LMNAMAPTNAAASMN1; SMN2CA1 | |
| SCHEMBL30888343 | 0.71 | NAAA (0.47) | LMNANAAASMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242327-B2 | Analgesic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2022-02-08 | — | — | US | disclosed |
| US-20200270221-A1 | ANALGESIC COMPOUNDS | KTHERA, LLC | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270221-A1 | ANALGESIC COMPOUNDS | INA, IK, ACHE | LMNA 3965/4885MAPT 2670/4885NAAA 2117/4885 |
| US-11242327-B2 | Analgesic compounds | INA, IK, ACHE | LMNA 3965/4885MAPT 2670/4885NAAA 2117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.