Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692592 | 0.84 | TRPA1 (0.46) | NUDT1CD274PTGS2TRPA1ATM | |
| SCHEMBL11203627 | 0.82 | PTGS2 (0.41) | HTR7PTGS2PTGS1TSHRALDH1A1 | |
| SCHEMBL9419202 | 0.82 | HTR7 (0.50) | HTR7TRPA1TSHRACHEALDH1A1 | |
| SCHEMBL10304805 | 0.82 | PTGS2 (0.46) | HTR7BRD4CREBBPCD274PTGS2 | |
| SCHEMBL15593264 | 0.82 | HTR7 (0.41) | HTR7BRD4CREBBPCD274PTGS2 | |
| SCHEMBL27449014 | 0.82 | TLR8 (0.57) | TRPA1ATMTLR8ALDH1A1 | |
| SCHEMBL31110225 | 0.81 | TRPA1 (0.44) | NUDT1CD274PTGS2TRPA1ATM | |
| SCHEMBL17125584 | 0.81 | S1PR1 (0.42) | HTR7BRD4CREBBPNUDT1ALDH1A1 | |
| SCHEMBL17125585 | 0.81 | S1PR1 (0.42) | HTR7BRD4CREBBPNUDT1ALDH1A1 | |
| SCHEMBL16453884 | 0.80 | HTR7 (0.40) | HTR7BRD4CREBBPCD274PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040732-B2 | Process for the production of biaryl compounds | DSM IP ASSETS B.V. (NL) | 2018-08-07 | — | — | US | disclosed |
| EP-3169651-B1 | PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS | DSM IP ASSETS BV (NL) | 2018-06-20 | — | — | EP | disclosed |
| US-20170210681-A1 | PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2017-07-27 | — | — | US | disclosed |
| WO-2017102944-A1 | PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2017-06-22 | — | — | WO | disclosed |
| EP-3169651-A1 | PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS | DSM IP Assets B.V. (NL) | 2017-05-24 | — | — | EP | disclosed |
| CN-104193580-B | Separating and purifying method for tetramethyl biphenyl isomer mixture | 哈尔滨工业大学（威海） | 2017-02-15 | — | — | CN | disclosed |
| US-9522857-B2 | 3,3′,4,4′-tetraalkyl cyclohexylbenzene and method for producing same | UBE INDUSTRIES, LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-9469621-B2 | Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| WO-2016008931-A1 | PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2016-01-21 | — | — | WO | disclosed |
| US-20150274689-A1 | METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN | UBE CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20130202871-A1 | POLYIMIDE SHEET AND MANUFACTURING METHOD THEREOF | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-08 | — | — | US | disclosed |
| US-8093348-B1 | Polyimides derived from novel asymmetric dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-7425650-B1 | Synthesis of asymmetric tetracarboxylic acids and corresponding dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2008-09-16 | — | — | US | disclosed |
| US-7381849-B1 | Synthesis of asymmetric tetracarboxylic acids and dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-06-03 | — | — | US | disclosed |
| US-6914152-B2 | Method for producing biphenyl and its derivatives | UBE INDUSTRIES, LTD. (JP) | 2005-07-05 | — | — | US | disclosed |
| US-20030088120-A1 | Method for producing biphenyl and its derivatives | UBE INDUSTRIES, LTD. (JP) | 2003-05-08 | — | — | US | disclosed |
| US-4937389-A | HEATING, MIXING WITH METHANOL, COOLING, CRYSTALLIZATION | AMOCO CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0349218-A2 | Separation of 3,3,',4,4'- and 2,3,3',4'-tetramethyldiphenyl ether | AMOCO CORPORATION (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4294976-A | DEHYDROGENATIVE DIMERIZATION IN THE PRESENCE OF OXALIC ACID AND A PALLADIUM CATALYST | UBE INDUSTRIES, LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| US-3940426-A | CRYSTALLIZATION OF ISOMERS | UBE INDUSTRIES, LTD. (JA) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210681-A1 | PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS | DDT, COASY, ALDH3A1 | HTR7 3874/4885BRD4 1322/4885CREBBP 4301/4885 |
| US-20030088120-A1 | Method for producing biphenyl and its derivatives | AOC1, AOC3, DDT | HTR7 2300/4885BRD4 352/4885CREBBP 3547/4885 |
| US-10040732-B2 | Process for the production of biaryl compounds | DDT, COASY, ALDH3A1 | HTR7 3874/4885BRD4 1322/4885CREBBP 4301/4885 |
| US-20150274689-A1 | METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN | DDT, CYP1A1, CYP1B1 | HTR7 3016/4885BRD4 116/4885CREBBP 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.