Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091653 | 0.89 | DGAT1 (0.61) | DGAT1HCRTR1HCRTR2BRD4ALDH1A1 | |
| SCHEMBL20291414 | 0.86 | BRD4 (0.66) | HCRTR1HCRTR2BRD4ALDH1A1MMP2 | |
| SCHEMBL13153064 | 0.82 | HCRTR1 (0.52) | DGAT1HCRTR1HCRTR2ALDH1A1MMP2 | |
| SCHEMBL20291408 | 0.82 | ALDH1A1 (0.58) | HCRTR1HCRTR2BRD4ALDH1A1MMP2 | |
| SCHEMBL20291410 | 0.81 | ALDH1A1 (0.69) | HCRTR1HCRTR2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20291390 | 0.81 | ALDH1A1 (0.65) | HCRTR1HCRTR2BRD4ALDH1A1L3MBTL1 | |
| SCHEMBL28962077 | 0.79 | ALDH1A1 (0.53) | HCRTR1HCRTR2ALDH1A1MMP2MMP9 | |
| SCHEMBL28926521 | 0.79 | ALDH1A1 (0.53) | HCRTR1HCRTR2ALDH1A1MMP2MMP9 | |
| SCHEMBL28926493 | 0.79 | ALDH1A1 (0.53) | HCRTR1HCRTR2ALDH1A1MMP2MMP9 | |
| SCHEMBL28926492 | 0.79 | ALDH1A1 (0.53) | HCRTR1HCRTR2ALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BAYER HEALTHCARE LLC (US) | 2010-01-21 | — | — | US | disclosed |
| EP-1912634-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Healthcare, LLC (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007016538-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BCAT2, BCAT1, FABP4 | DGAT1 2018/4885HCRTR1 912/4885HCRTR2 832/4885 |
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BCAT2, BCAT1, FABP4 | DGAT1 2018/4885HCRTR1 912/4885HCRTR2 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.