SCHEMBL32664935

C[C@@H]1O[C@@H](OCCNC(=O)CN(CC(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](CCCCNC(=O)CN(CC(=O)NCCCCCNC(=O)CN(CC(=O)NCCCCCC(=O)OCc2ccccc2)CC(=O)NCCO[C@H]2O[C@H](CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)CC(=O)NCCO[C@H]2O[C@H](C)[C@H](O)[C@H](O)[C@H]2O)C(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	MMP13	P45452	2/20	0.40

▸	LGALS8	O00214	1/20	0.37

▸	ALDH1A1	P00352	1/20	0.36

▸	CYP3A4	P08684	1/20	0.36

▸	ALOX15	P16050	1/20	0.36

▸	MAPK1	P28482	1/20	0.36

▸	HSD17B10	Q99714	1/20	0.36

▸	FGF1	P05230	2/20	0.36

▸	FGF2	P09038	2/20	0.36

▸	VEGFA	P15692	2/20	0.36

▸	HPSE	Q9Y251	2/20	0.36

▸	CD209	Q9NNX6	1/20	0.35

▸	SELP	P16109	3/20	0.35

▸	SELE	P16581	1/20	0.35

▸	EPOR	P19235	4/20	0.35

▸	MMP2	P08253	1/20	0.34

▸	MMP3	P08254	1/20	0.34

▸	MMP9	P14780	1/20	0.34

▸	MMP12	P39900	1/20	0.34

▸	SIRT2	Q8IXJ6	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30891384	1.00	MMP13 (0.40)	MMP13LGALS8ALDH1A1CYP3A4ALOX15
SCHEMBL30891466	0.99	MMP13 (0.41)	MMP13LGALS8ALDH1A1CYP3A4ALOX15
SCHEMBL30891315	0.99	MMP13 (0.41)	MMP13LGALS8ALDH1A1CYP3A4ALOX15
SCHEMBL30891367	0.95	MMP13 (0.42)	MMP13LGALS8FGF1FGF2VEGFA
SCHEMBL30891493	0.90	MMP13 (0.41)	MMP13LGALS8ALDH1A1CYP3A4ALOX15
SCHEMBL32664918	0.89	MMP13 (0.40)	MMP13ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL30891399	0.89	MMP13 (0.41)	MMP13LGALS8ALDH1A1CYP3A4ALOX15
SCHEMBL30891326	0.88	MMP13 (0.41)	MMP13LGALS8ALDH1A1CYP3A4ALOX15
SCHEMBL30891448	0.88	MMP13 (0.42)	MMP13ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL30891411	0.88	MMP13 (0.42)	MMP13ALDH1A1CYP3A4ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20260021190-A1	GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES	MERCK SHARP & DOHME LLC (US)	2026-01-22	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20260021190-A1	GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES	INSR, GPR119, GLP1R	MMP13 1271/4885LGALS8 615/4885ALDH1A1 2398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.