Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 8/20 | 0.44 |
| ▸ | BRAF | P15056 | 8/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30894571 | 0.89 | RXRA (0.72) | RXRAMAPTSMG1ALDH1A1NPC1 | |
| SCHEMBL30894577 | 0.89 | CDK1 (0.50) | RXRAMAPTCDK1CDK2SMG1 | |
| SCHEMBL30894572 | 0.88 | RXRA (0.66) | RXRAMAPTCDK1CDK2SMG1 | |
| SCHEMBL30894568 | 0.88 | RXRA (0.66) | RXRAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30366946 | 0.85 | RXRA (0.82) | RXRAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30894582 | 0.81 | RXRA (0.55) | RXRAMAPTCDK1CDK2SMG1 | |
| SCHEMBL30894580 | 0.78 | RXRA (0.54) | RXRAMAPTALDH1A1 | |
| SCHEMBL30894579 | 0.77 | RXRA (0.80) | RXRAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30367547 | 0.75 | RXRA (0.82) | RXRANPC1RAB9ASMN1; SMN2PIM2 | |
| SCHEMBL30894587 | 0.74 | NPC1 (0.46) | RXRAMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645568-A | N- ([ 4,4' -bipyridine ] -2-yl) cinnamamide derivative, and preparation and application thereof | 厦门大学 | 2024-03-05 | — | — | CN | disclosed |