Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.41 |
| ▸ | ITGAL | P20701 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366603 | 0.93 | RXRA (0.71) | RXRANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30366946 | 0.90 | RXRA (0.82) | RXRANPC1RAB9ASMN1; SMN2ITGB2 | |
| SCHEMBL30366881 | 0.84 | RXRA (0.85) | RXRANPC1RAB9ASMN1; SMN2ITGB2 | |
| SCHEMBL30366740 | 0.81 | RXRA (0.58) | RXRAITGB2ICAM1ITGALKMT2A | |
| SCHEMBL30894579 | 0.80 | RXRA (0.80) | RXRANPC1RAB9ASMN1; SMN2ITGB2 | |
| SCHEMBL30894568 | 0.79 | RXRA (0.66) | RXRANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL30894572 | 0.79 | RXRA (0.66) | RXRANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29083757 | 0.78 | RXRA (0.60) | RXRARAB9ASMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL30367152 | 0.75 | WNT3A (0.54) | RXRA | |
| SCHEMBL30894584 | 0.75 | RXRA (0.59) | RXRANPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |