Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | IL1B | P01584 | 8/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620217 | 0.83 | NLRP3 (0.80) | NLRP3KCNH2IL1BTNFCNR1 | |
| SCHEMBL31679496 | 0.83 | NLRP3 (0.66) | NLRP3KCNH2IL1BTNFCNR1 | |
| SCHEMBL30041647 | 0.82 | NLRP3 (1.00) | NLRP3KCNH2IL1BTNF | |
| Hydrochloric Acid SCHEMBL30041699 | 0.81 | NLRP3 (0.98) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30895755 | 0.78 | KCNH2 (0.36) | NLRP3KCNH2CACNA1B | |
| SCHEMBL27224457 | 0.77 | NLRP3 (0.62) | NLRP3KCNH2IL1BTNFCNR1 | |
| SCHEMBL30932818 | 0.77 | NLRP3 (0.62) | NLRP3KCNH2IL1BTNFCNR1 | |
| SCHEMBL30157241 | 0.75 | NLRP3 (0.54) | NLRP3KCNH2IL1BTNFCCR2 | |
| SCHEMBL30932875 | 0.75 | NLRP3 (0.59) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL27224470 | 0.75 | NLRP3 (0.59) | NLRP3KCNH2IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024090469-A1 | FUSED PYRIDAZINE DERIVATIVE | アステラス製薬株式会社 | 2024-05-02 | — | — | WO | disclosed |