Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.47 |
| ▸ | MERTK | Q12866 | 3/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224032 | 1.00 | CAMK2D (0.49) | CAMK2DCDK2MAPKAPK2MERTKIDH2 | |
| SCHEMBL30896197 | 0.88 | PAK4 (0.56) | CAMK2DMERTKCHEK2PAK4SOS1 | |
| SCHEMBL27223450 | 0.88 | PAK4 (0.56) | CAMK2DMERTKCHEK2PAK4SOS1 | |
| SCHEMBL30896236 | 0.88 | MERTK (0.56) | CAMK2DMERTKPAK4NTRK1SOS1 | |
| SCHEMBL27223397 | 0.88 | MERTK (0.56) | CAMK2DMERTKPAK4NTRK1SOS1 | |
| SCHEMBL27223370 | 0.79 | MERTK (0.64) | CAMK2DMERTKPAK4SOS1 | |
| SCHEMBL27223559 | 0.78 | CAMK2D (0.64) | CAMK2DMERTKIDH2CHEK2PAK4 | |
| SCHEMBL30896205 | 0.78 | MERTK (0.56) | CAMK2DMERTKSOS1 | |
| SCHEMBL27224039 | 0.78 | MERTK (0.56) | CAMK2DMERTKSOS1 | |
| SCHEMBL27223952 | 0.77 | MERTK (0.55) | CAMK2DMERTKSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | CAMK2D 389/4885CDK2 2243/4885MAPKAPK2 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.