SCHEMBL30896647

SCHEMBL30896647

O=S1(=O)N=C(Oc2ccc(OCc3ccccc3)cc2)c2ccccc21

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
GAA P10253 4/20 0.64
HTT P42858 1/20 0.64
PKM P14618 1/20 0.54
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
RECQL P46063 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
GSTP1 P09211 1/20 0.44
CYP1A2 P05177 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7738030 0.77 ALDH1A1 (0.79) ALDH1A1GAAHTTPKMHSD17B10
SCHEMBL11343161 0.76 PKM (0.61) ALDH1A1GAAHTTPKMHSD17B10
SCHEMBL5538712 0.72 LMNA (0.72) GAALMNAMAPTL3MBTL1NR4A1
SCHEMBL17594448 0.70 GSTP1 (0.58) GAALMNAMAPTL3MBTL1NR4A1
SCHEMBL8437480 0.70 PKM (1.00) ALDH1A1GAAHTTPKMHSD17B10
SCHEMBL11849334 0.70 LMNA (0.69) GAALMNAMAPTL3MBTL1NR4A1
SCHEMBL27367676 0.70 LMNA (0.82) GAALMNAMAPTL3MBTL1NR4A1
SCHEMBL339813 0.70 LMNA (0.82) GAALMNAMAPTL3MBTL1NR4A1
SCHEMBL30896648 0.69 ALDH1A1 (0.70) ALDH1A1GAAHTTPKMHSD17B10
SCHEMBL30896636 0.69 ALDH1A1 (0.64) ALDH1A1GAAHTTPKMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024085725-A1 NOVEL COMPOUND DERIVATIVE AND PHARMACOLOGICAL USE THEREOF 고려대학교 산학협력단 2024-04-25 WO claimed