SCHEMBL30896648

SCHEMBL30896648

O=S1(=O)N=C(Oc2cccc(Br)c2)c2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.70
GAA P10253 3/20 0.62
KDM4E B2RXH2 2/20 0.62
HSD17B10 Q99714 2/20 0.62
THRB P10828 1/20 0.62
ALOX15 P16050 1/20 0.62
RECQL P46063 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
HTT P42858 1/20 0.59
MAPT P10636 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 1/20 0.52
EPAS1 Q99814 2/20 0.52
PKM P14618 1/20 0.49
EGFR P00533 1/20 0.39
RAB9A P51151 1/20 0.38
KCNA3 P22001 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30896649 0.81 ALDH1A1 (0.67) ALDH1A1GAAKDM4EHSD17B10THRB
SCHEMBL7738030 0.79 ALDH1A1 (0.79) ALDH1A1GAAKDM4EHSD17B10THRB
SCHEMBL30896636 0.73 ALDH1A1 (0.64) ALDH1A1GAAKDM4EHSD17B10THRB
SCHEMBL7634824 0.72 EPAS1 (0.56) ALDH1A1GAAKDM4EMAPTNPSR1
SCHEMBL11131431 0.70 LMNA (0.84) ALDH1A1GAAKDM4EHSD17B10THRB
SCHEMBL11024449 0.70 HSD17B10 (0.71) ALDH1A1GAAKDM4EHSD17B10THRB
SCHEMBL30896647 0.69 ALDH1A1 (0.71) ALDH1A1GAAKDM4EHSD17B10THRB
SCHEMBL457828 0.68 MAOB (0.54) ALDH1A1GAAMAPTEGFRABCG2
SCHEMBL5434 0.66 LTA4H (0.57) ALDH1A1GAATDP1HTTMAPT
SCHEMBL30020579 0.66 LTA4H (0.57) ALDH1A1GAATDP1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024085725-A1 NOVEL COMPOUND DERIVATIVE AND PHARMACOLOGICAL USE THEREOF 고려대학교 산학협력단 2024-04-25 WO claimed