Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910103 | 0.87 | PKM (0.77) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL6243131 | 0.84 | PKM (0.72) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL11024449 | 0.80 | HSD17B10 (0.71) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL8439404 | 0.80 | PKM (0.66) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL7738030 | 0.80 | ALDH1A1 (0.79) | PKMALDH1A1GAAHSD17B10LMNA | |
| Probenazol SCHEMBL23516 | 0.79 | PKM (0.65) | PKMALDH1A1GAAHSD17B10LMNA | |
| Probenazol SCHEMBL30425932 | 0.79 | PKM (0.65) | PKMALDH1A1GAAHSD17B10LMNA | |
| Probenazol SCHEMBL8409812 | 0.79 | PKM (0.65) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL10910212 | 0.78 | PKM (0.63) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL10910315 | 0.78 | PKM (0.63) | PKMALDH1A1GAAHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952282-A | ADDING A 1,1-DIOXIDE, 3-(SUBSTITUTED AMINO)-1,2-BENZOISOTHIAZOLE COMPOUND TO BLEACH AS A BLEACH CATALYST | CLARIANT GMBH (DE) | 1999-09-14 | — | — | US | disclosed |