SCHEMBL30898286

SCHEMBL30898286

CC(C)(C)NC(=O)OCCCc1cccc(CO)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP4F2 P78329 3/20 0.41
CYP4A11 Q02928 3/20 0.41
LMNA P02545 1/20 0.40
CTSK P43235 1/20 0.39
NAAA Q02083 3/20 0.39
CHRNA7 P36544 1/20 0.39
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
FKBP1A P62942 1/20 0.38
REN P00797 1/20 0.38
PPARG P37231 2/20 0.38
PPARA Q07869 2/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898243 0.92 MGLL (0.43) NPC1RAB9ARECQLSMN1; SMN2CYP4F2
SCHEMBL27611273 0.84 NPC1 (0.63) NPC1RAB9ARECQLSMN1; SMN2LMNA
SCHEMBL2208843 0.84 CYP2D6 (0.45) NPC1RAB9ARECQLSMN1; SMN2FKBP1A
SCHEMBL27642716 0.83 PRKCA (0.44) NPC1RAB9ASMN1; SMN2LMNAPDK1
SCHEMBL28176109 0.82 NAAA (0.42) NPC1RAB9ARECQLSMN1; SMN2CYP4F2
SCHEMBL29278320 0.80 NPC1 (0.57) NPC1RAB9ARECQLSMN1; SMN2LMNA
SCHEMBL613990 0.80 CYP4F2 (0.39) NPC1RAB9ARECQLSMN1; SMN2CYP4F2
SCHEMBL27832828 0.80 LOXL2 (0.46) NPC1RAB9ASMN1; SMN2CYP4F2CYP4A11
SCHEMBL28776560 0.78 TYR (0.53)
SCHEMBL30898281 0.78 CYP4F2 (0.49) NPC1RAB9ARECQLSMN1; SMN2CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105159-A1 LIGANDS OF THE M6A-RNA READERS UNIVERSITY OF ZURICH (CH) 2024-05-23 WO disclosed