Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31470889 | 0.78 | EPHX1 (0.35) | NPC1GPR119 | |
| SCHEMBL25334904 | 0.75 | HSD17B10 (0.44) | HSD17B10HSD11B1NPC1KDM1ALMNA | |
| SCHEMBL27990166 | 0.74 | GHSR (0.36) | NPC1KDM1AUCHL1GPR119 | |
| SCHEMBL25970274 | 0.72 | HSD17B10 (0.46) | HSD17B10HSD11B1NPC1KDM1ALMNA | |
| SCHEMBL25983994 | 0.71 | HSD17B10 (0.45) | HSD17B10HSD11B1NPC1KDM1ALMNA | |
| SCHEMBL692983 | 0.70 | HSD17B10 (0.41) | HSD17B10HSD11B1NPC1KDM1ALMNA | |
| SCHEMBL1488763 | 0.70 | HSD17B10 (0.41) | HSD17B10HSD11B1NPC1KDM1ALMNA | |
| SCHEMBL25970571 | 0.69 | UCHL1 (0.47) | HSD17B10HSD11B1NPC1KDM1ALMNA | |
| SCHEMBL24693398 | 0.69 | HSD11B1 (0.41) | HSD17B10HSD11B1NPC1KDM1AHPGD | |
| SCHEMBL20558459 | 0.69 | HSD11B1 (0.41) | HSD17B10HSD11B1NPC1KDM1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |