Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970607 | 0.82 | KDM1A (0.52) | UCHL1NPC1KDM1AMEN1KMT2A | |
| SCHEMBL28521198 | 0.82 | HSD17B10 (0.48) | UCHL1NPC1MEN1KMT2AHSD11B1 | |
| SCHEMBL22725293 | 0.82 | HSD17B10 (0.48) | UCHL1NPC1MEN1KMT2AHSD11B1 | |
| SCHEMBL22725305 | 0.82 | HSD17B10 (0.48) | UCHL1NPC1MEN1KMT2AHSD11B1 | |
| SCHEMBL25970105 | 0.80 | HSD17B10 (0.50) | UCHL1NPC1MEN1KMT2AHSD11B1 | |
| SCHEMBL25970081 | 0.80 | HSD17B10 (0.50) | UCHL1NPC1MEN1KMT2AHSD11B1 | |
| SCHEMBL25970131 | 0.79 | HSD17B10 (0.49) | UCHL1NPC1MEN1KMT2AHSD11B1 | |
| SCHEMBL25970274 | 0.76 | HSD17B10 (0.46) | NPC1KDM1AHSD11B1LMNANPSR1 | |
| SCHEMBL18642714 | 0.75 | RIPK1 (0.69) | NPC1MEN1KMT2ALMNARIPK1 | |
| SCHEMBL6960066 | 0.75 | RIPK1 (0.69) | NPC1MEN1KMT2ALMNARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | UCHL1 506/4885NPC1 3712/4885KDM1A 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.