Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 5/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472402 | 1.00 | TRPV4 (0.53) | TRPV4KIF11SLC22A12PDK1PDK2 | |
| SCHEMBL8576403 | 0.86 | TRPV4 (0.44) | TRPV4KIF11SLC22A12PDK1PDK2 | |
| SCHEMBL628094 | 0.84 | TRPV4 (0.57) | TRPV4KIF11SLC22A12PDK1PDK2 | |
| SCHEMBL7569957 | 0.81 | TRPV4 (0.58) | TRPV4KIF11SLC22A12PDK2AR | |
| SCHEMBL12203355 | 0.80 | PDK1 (0.43) | TRPV4KIF11SLC22A12PDK1PDK2 | |
| SCHEMBL10766551 | 0.80 | KDR (0.40) | TRPV4KIF11SLC22A12PDK1FAAH | |
| SCHEMBL1727083 | 0.78 | KIF11 (0.73) | TRPV4KIF11SLC22A12AR | |
| SCHEMBL5203682 | 0.78 | KIF11 (0.53) | TRPV4KIF11SLC22A12AR | |
| SCHEMBL30168580 | 0.78 | KIF11 (0.73) | TRPV4KIF11SLC22A12AR | |
| SCHEMBL7374120 | 0.77 | PDK1 (0.48) | TRPV4KIF11SLC22A12PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264724-A1 | MPRO INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-26 | — | — | WO | disclosed |
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |