Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.73 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168580 | 1.00 | KIF11 (0.73) | KIF11TRPV4CYP3A4CYP3A5KDM1A | |
| SCHEMBL8574981 | 0.86 | KIF11 (0.56) | KIF11TRPV4CYP3A4CYP3A5 | |
| SCHEMBL17888539 | 0.84 | KIF11 (0.54) | KIF11TRPV4CYP3A4CYP3A5SLC22A12 | |
| SCHEMBL5358402 | 0.84 | KIF11 (0.54) | KIF11TRPV4CYP3A4CYP3A5 | |
| SCHEMBL29421437 | 0.83 | KIF11 (0.58) | KIF11TRPV4CYP3A4CYP3A5SLC22A12 | |
| SCHEMBL185191 | 0.83 | KIF11 (0.58) | KIF11TRPV4CYP3A4CYP3A5SLC22A12 | |
| SCHEMBL7569957 | 0.83 | TRPV4 (0.58) | KIF11TRPV4CYP3A4CYP3A5SLC22A12 | |
| SCHEMBL12203344 | 0.82 | KIF11 (0.51) | KIF11TRPV4CYP3A4CYP3A5SLC22A12 | |
| SCHEMBL2636950 | 0.81 | KIF11 (0.51) | KIF11TRPV4CYP3A4CYP3A5SLC22A12 | |
| SCHEMBL6209867 | 0.79 | KIF11 (0.53) | KIF11KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206469-A | Synthesis method of 3-hydroxy-4- (trifluoromethyl) benzonitrile | 峰成医药科技(天津)有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-114230486-A | Preparation method of 2-fluoro-4-cyano benzotrifluoride | 阜新金特莱氟化学有限责任公司 | 2022-03-25 | — | — | CN | claimed |
| CN-112979498-A | Preparation method of 3-fluoro-4-trifluoromethyl benzonitrile | 内蒙古蓝科生物科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| CN-101337911-A | Method for preparing 3-fluor-4-trifluoromethylbenzonitrile | FUXIN CUSTCHEM FINE CHEMICAL C (CN) | 2009-01-07 | — | — | CN | claimed |
| EP-0594317-B1 | Cyanoacrylate adhesives with improved cured thermal properties utilizing substituted aromatic additive | LOCTITE CORP (US) | 1997-09-03 | — | — | EP | claimed |
| US-5288794-A | Benzene compounds substituted with two or more electron withdrawing groups and one or more leaving groups delay onset of thermal decomposition | LOCTITE CORPORATION (US) | 1994-02-22 | — | — | US | claimed |
| EP-3887359-B1 | NOVEL TETRAZINE COMPOUNDS FOR IN VIVO IMAGING | UNIV COPENHAGEN (DK) | 2026-05-06 | — | — | EP | disclosed |
| CN-118206469-A | Synthesis method of 3-hydroxy-4- (trifluoromethyl) benzonitrile | 峰成医药科技(天津)有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118206469-A | Synthesis method of 3-hydroxy-4- (trifluoromethyl) benzonitrile | 峰成医药科技(天津)有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| EP-4157823-A1 | COMPOUNDS | JANSSEN Pharmaceutica NV (BE) | 2023-04-05 | — | — | EP | disclosed |
| WO-2005054176-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
| WO-2005044784-A1 | AMIDOACETONITRILE DERIVATIVES | NOVARTIS AG (CH) | 2005-05-19 | — | — | WO | disclosed |
| US-20040198736-A1 | Non-nucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC | 2004-10-07 | — | — | US | disclosed |
| WO-2004085406-A1 | BENZYL-PYRIDAZINONS AS REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004052845-A1 | TETRAHYDRO-NAPHTHALENE DERIVATIVES AS VANILLOID RECEPTOR ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | disclosed |
| EP-0594317-B1 | Cyanoacrylate adhesives with improved cured thermal properties utilizing substituted aromatic additive | LOCTITE CORP (US) | 1997-09-03 | — | — | EP | disclosed |
| US-5288794-A | Benzene compounds substituted with two or more electron withdrawing groups and one or more leaving groups delay onset of thermal decomposition | LOCTITE CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | KIF11 4532/4885TRPV4 832/4885CYP3A4 490/4885 |
| US-20040198736-A1 | Non-nucleoside reverse transcriptase inhibitors | POLR1A, POLR2A, POLR2E | KIF11 3125/4885TRPV4 4668/4885CYP3A4 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.