Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899301 | 0.84 | TRPV4 (0.53) | TRPV4NOTUMSLC22A12KIF11VCAM1 | |
| SCHEMBL472402 | 0.84 | TRPV4 (0.53) | TRPV4NOTUMSLC22A12KIF11VCAM1 | |
| SCHEMBL365180 | 0.81 | AR (0.60) | NOTUMKIF11KDREPHX2AR | |
| SCHEMBL7569957 | 0.81 | TRPV4 (0.58) | TRPV4SLC22A12KIF11ARPDK2 | |
| SCHEMBL16663958 | 0.80 | TRPV4 (0.45) | TRPV4SLC22A12KIF11VCAM1AR | |
| SCHEMBL16961215 | 0.80 | IDO1 (0.43) | TRPV4NOTUMIDO1HTR3EHTR3B | |
| SCHEMBL2520644 | 0.80 | KDR (0.51) | TRPV4NOTUMIDO1HTR3EHTR3B | |
| SCHEMBL3457978 | 0.80 | IDO1 (0.43) | TRPV4NOTUMSLC22A12IDO1HTR3E | |
| SCHEMBL2944512 | 0.80 | PYCR1 (0.46) | TRPV4NOTUMSLC22A12IDO1HTR3E | |
| SCHEMBL7604551 | 0.79 | TRPV4 (0.56) | TRPV4SLC22A12KIF11ARPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799625-B | Organic molecules, in particular for optoelectronic devices | 辛诺拉有限公司 | 2021-12-14 | — | — | CN | claimed |
| US-20200399256-A1 | ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-12-24 | — | — | US | claimed |
| EP-3642302-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2020-10-21 | — | — | EP | claimed |
| EP-3642302-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | cynora GmbH (DE) | 2020-04-29 | — | — | EP | claimed |
| CN-110799625-A | Organic molecules, in particular for optoelectronic devices | 辛诺拉有限公司 | 2020-02-14 | — | — | CN | claimed |
| WO-2019001838-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-01-03 | — | — | WO | claimed |
| US-4822903-A | Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-04-18 | — | — | US | claimed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | claimed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | claimed |
| WO-2025264724-A1 | MPRO INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-26 | — | — | WO | disclosed |
| CN-118652153-A | Method for synthesizing organic nitrile compound from aldehyde | 国科大杭州高等研究院 | 2024-09-17 | — | — | CN | disclosed |
| US-11634391-B2 | Compounds which are inhibitors of Notum | UCL BUSINESS LTD (GB) | 2023-04-25 | — | — | US | disclosed |
| CN-114539141-A | Preparation method of sorafenib | 南京焕然生物科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110799625-B | Organic molecules, in particular for optoelectronic devices | 辛诺拉有限公司 | 2021-12-14 | — | — | CN | disclosed |
| US-4504595-A | Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-03-12 | — | — | US | disclosed |
| US-4493800-A | REACTING A TRIFLUOROMETHYLHALOGENOBENZENE WITH COPPER CYANIDE | DAIKIN KOGYO CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | disclosed |
| EP-0097357-A1 | Process for preparing trifluoromethylbenzene derivatives | Daikin Kogyo Co., Ltd. (JP) | 1984-01-04 | — | — | EP | disclosed |
| US-4178383-A | Fungicidally active oxime-ethers of isonitrosocyanoacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634391-B2 | Compounds which are inhibitors of Notum | NOTUM, GOT2, GOT1 | TRPV4 4525/4885NOTUM 1/4885SLC22A12 2280/4885 |
| US-20200399256-A1 | ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | OR10J3, ORC3, AOC3 | TRPV4 366/4885NOTUM 1783/4885SLC22A12 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.