Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949149 | 0.82 | DGAT1 (0.36) | DGAT1UCHL1LIPEHIF1AGSK3A | |
| SCHEMBL20520117 | 0.79 | FFAR1 (0.33) | UCHL1GSK3AGSK3B | |
| SCHEMBL22445348 | 0.78 | LPL (0.33) | UCHL1GSK3AGSK3B | |
| SCHEMBL9943204 | 0.77 | LIPE (0.40) | DGAT1UCHL1LIPEKDM4EALDH1A1 | |
| SCHEMBL29653311 | 0.77 | LIPE (0.40) | DGAT1UCHL1LIPEKDM4EALDH1A1 | |
| SCHEMBL24667122 | 0.77 | UCHL1 (0.36) | DGAT1UCHL1LIPEHIF1AGSK3A | |
| SCHEMBL28360858 | 0.77 | DGAT1 (0.35) | DGAT1UCHL1LIPEHIF1AGSK3A | |
| SCHEMBL14712147 | 0.76 | ALDH1A1 (0.43) | DGAT1UCHL1KDM4EALDH1A1HIF1A | |
| SCHEMBL14809578 | 0.76 | DGAT1 (0.55) | DGAT1HIF1AGSK3AGSK3BCXCR2 | |
| SCHEMBL29665108 | 0.76 | DGAT1 (0.55) | DGAT1HIF1AGSK3AGSK3BCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |