Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.33 |
| ▸ | METAP1 | P53582 | 5/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090768 | 1.00 | METAP2 (0.33) | METAP2METAP1FDPSBHMTTSHR | |
| SCHEMBL2989547 | 0.86 | ECE1 (0.36) | METAP2METAP1FDPSBHMTTSHR | |
| SCHEMBL2989543 | 0.86 | ECE1 (0.36) | METAP2METAP1FDPSBHMTTSHR | |
| SCHEMBL3106035 | 0.84 | CA12 (0.38) | TSHRCA12CA9 | |
| SCHEMBL3106026 | 0.84 | CA12 (0.38) | TSHRCA12CA9 | |
| SCHEMBL3096008 | 0.82 | METAP2 (0.35) | METAP2METAP1TSHRCA12CA9 | |
| SCHEMBL3098115 | 0.82 | FDPS (0.42) | METAP1FDPS | |
| SCHEMBL3098107 | 0.82 | FDPS (0.42) | METAP1FDPS | |
| SCHEMBL4341296 | 0.78 | LAP3 (0.40) | METAP1FDPSCA12CA9 | |
| SCHEMBL3098289 | 0.76 | MME (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |