Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106026 | 1.00 | CA12 (0.38) | CA12CA9TSHRCA2CA1 | |
| SCHEMBL2991039 | 0.85 | ALDH1A1 (0.43) | TSHRCA2CA1RNPEPALDH1A1 | |
| SCHEMBL2991041 | 0.85 | ALDH1A1 (0.43) | TSHRCA2CA1RNPEPALDH1A1 | |
| SCHEMBL3090764 | 0.84 | METAP2 (0.33) | CA12CA9TSHR | |
| SCHEMBL3090768 | 0.84 | METAP2 (0.33) | CA12CA9TSHR | |
| SCHEMBL3098107 | 0.81 | FDPS (0.42) | CA2CA1 | |
| SCHEMBL3098115 | 0.81 | FDPS (0.42) | CA2CA1 | |
| Racemethionine SCHEMBL27772074 | 0.80 | BHMT (0.44) | CA2CA1ALDH1A1NPSR1LMNA | |
| SCHEMBL3087428 | 0.80 | CA12 (0.37) | CA12CA9TSHRCA2CA1 | |
| SCHEMBL3098286 | 0.79 | MME (0.32) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |