Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908222 | 0.92 | METAP1 (0.38) | METAP1SCN9ACYP17A1TOP2ATOP2B | |
| SCHEMBL30908271 | 0.87 | PTPN1 (0.36) | SCN9ATOP2ATOP2BAKT1 | |
| SCHEMBL30908217 | 0.83 | GSK3B (0.37) | SCN9ACYP17A1TOP2ATOP2BGSK3B | |
| SCHEMBL30908391 | 0.83 | TOP2A (0.35) | SCN9ACYP17A1TOP2ATOP2BGSK3B | |
| SCHEMBL30908442 | 0.82 | AURKA (0.37) | SCN9ACYP17A1TOP2ATOP2BHDAC1 | |
| SCHEMBL30908483 | 0.82 | TSPO (0.39) | SCN9ATOP2ATOP2BHDAC1AKT1 | |
| SCHEMBL30908503 | 0.81 | NPC1 (0.35) | SCN9ATOP2ATOP2BCYP2C9PTGER1 | |
| SCHEMBL30908418 | 0.81 | SCN9A (0.41) | SCN9ATOP2ATOP2BAKT1 | |
| SCHEMBL30908423 | 0.81 | SCN9A (0.41) | SCN9ATOP2ATOP2BAKT1 | |
| SCHEMBL30908240 | 0.79 | GSK3B (0.37) | SCN9ACYP17A1GSK3BDYRK1AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |