Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908418 | 1.00 | SCN9A (0.41) | SCN9AHTR2CSLC6A4NPY2RCCR2 | |
| SCHEMBL30908572 | 0.91 | SCN9A (0.35) | SCN9AHTR2CSLC6A4NPY2RCCR2 | |
| SCHEMBL30908271 | 0.86 | PTPN1 (0.36) | SCN9AMEN1KMT2AAKT1ALDH1A1 | |
| SCHEMBL30908391 | 0.85 | TOP2A (0.35) | SCN9AMEN1KMT2AAKT1ALDH1A1 | |
| SCHEMBL30908503 | 0.83 | NPC1 (0.35) | SCN9ACCR2TOP2ATOP2B | |
| SCHEMBL30908442 | 0.82 | AURKA (0.37) | SCN9AAKT1ALDH1A1TSHRTOP2A | |
| SCHEMBL30908483 | 0.82 | TSPO (0.39) | SCN9ACCR2KMT2AAKT1ALDH1A1 | |
| SCHEMBL30908158 | 0.81 | METAP1 (0.39) | SCN9AAKT1TOP2ATOP2B | |
| SCHEMBL30908405 | 0.81 | HDAC1 (0.35) | SCN9ATOP2ATOP2B | |
| SCHEMBL30908222 | 0.79 | METAP1 (0.38) | SCN9AALDH1A1TSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |