Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908572 | 0.88 | SCN9A (0.35) | CA2CA1CA12CA9SCN9A | |
| SCHEMBL30908391 | 0.87 | TOP2A (0.35) | NPC1RAB9ASCN9AHDAC1TOP2A | |
| SCHEMBL30908442 | 0.86 | AURKA (0.37) | NPC1RAB9ASCN9AHDAC1TOP2A | |
| SCHEMBL30908271 | 0.86 | PTPN1 (0.36) | NPC1RAB9ASCN9ATOP2ATOP2B | |
| SCHEMBL30908483 | 0.85 | TSPO (0.39) | NPC1RAB9ASCN9AHDAC1TOP2A | |
| SCHEMBL30908405 | 0.84 | HDAC1 (0.35) | SCN9AHDAC1TOP2ATOP2B | |
| SCHEMBL30908418 | 0.83 | SCN9A (0.41) | SCN9ATOP2ATOP2BCCR2 | |
| SCHEMBL30908423 | 0.83 | SCN9A (0.41) | SCN9ATOP2ATOP2BCCR2 | |
| SCHEMBL30908158 | 0.81 | METAP1 (0.39) | SCN9AHDAC1TOP2ATOP2BCYP2C9 | |
| SCHEMBL30908517 | 0.81 | NOS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |